The HELM (Hierarchical Editing Language for Macromolecules) 2.0 project has published an RFP that aims to implement a number of enhancements to the current HELM definition and open source codebase.
Having won the 2014 Best Practice Award at the Bio-IT World Conference & Expo, HELM again attracted plenty of attention at this year’s meeting (Boston, April 21-23 2015). Numerous contributions gave an overview of the growing HELM ecosystem and its adoption by the pharmaceutical industry.
The release of the HELM Editor by the Pistoia Alliance in 2014 inspired a team at Roche and quattro research to use this technology for the registration of antibodies engineered at Roche’s research sites.
ChEMBL 20 incorporates the Hierarchical Editing Language for Macromolecules (HELM), the macromolecular representation standard recently released by the Pistoia Alliance.
ChemAxon, a Pistoia Alliance member, has today released its new Biomolecule Toolkit product. The Biomolecule Toolkit includes HELM compatibility making it fully interoperable with an increasing number of other HELM-aware solutions and adopters.
The Pistoia Alliance HELM project started almost two years ago in December 2012 when David Klatte proposed that the Pistoia Alliance help open source a technology first developed for internal use at Pfizer. That technology was HELM and it enabled the representation of complex macromolecules. The Pistoia Alliance membership enthusiastically embraced the idea and the HELM project was born.
HELM addresses a problem at the root level of drug discovery. Pharmaceutical and biotech companies are looking at increasingly complex molecules in the search for new therapeutics, testing out RNA- and peptide-based compounds that tap directly into cellular pathways.
The video of the webinar is now available (also on the project's resources page). Slide decks of each talk can downloaded from this page.
The Pistoia Alliance and quattro research are pleased to announce the release of an extension to the HELM biomolecular representation standard.