The Pistoia Alliance HELM project started almost two years ago in December 2012 when David Klatte proposed that the Pistoia Alliance help open source a technology first developed for internal use at Pfizer. That technology was HELM and it enabled the representation of complex macromolecules. The Pistoia Alliance membership enthusiastically embraced the idea and the HELM project was born.

HELM addresses a problem at the root level of drug discovery. Pharmaceutical and biotech companies are looking at increasingly complex molecules in the search for new therapeutics, testing out RNA- and peptide-based compounds that tap directly into cellular pathways.

The video of the webinar is now available (also on the project's resources page). Slide decks of each talk can downloaded from this page.

HELM wins BioIT World Best Practices Award for Informatics! Congratulations to the whole team.

It was great to see so many of you at the HELM reception at BioIT World. For those who are unable to make it, here are the slides containing the latest news from the project and new HELM implementations.