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Case Study on the Sequence Services Project from the Pistoia Alliance

The objective of this project is to define standards for the provision of secure access to pre-competitive databases and software tools and invite external suppliers to provide those services to multiple consumers who would effectively share the cost of the maintenance. Such an approach liberates each bioscience company to concentrate their investments where they feel they have a competitive advantage.

Sequence Squeeze: An Open Contest for Sequence Compression

Next-generation sequencing machines produce large quantities of data which are becoming increasingly difficult to move between collaborating organisations or even store within a single organisation. Compressing the data to assist with this is vital, but existing techniques do not perform as well as might be expected. The need for a new compression technique was identified by the Pistoia Alliance who commissioned an open innovation contest to find one. The dynamic and interactive nature of the contest led to some novel algorithms and a high level of competition between participants.

The Pistoia Alliance Sequence Services Project

Life science researchers face duplicated efforts and fragmented workflows, so creating shared standards and secure, flexible external services—such as for sequence data—can streamline R&D, reduce costs, and boost innovation while addressing critical security and usability concerns.