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Data Driven Value

Webinar

Delivering Data Driven Value

Enhancing Access to Clinical Trial Data for Secondary Use

At the Pistoia Alliance, we are exploring how the FAIRification of such data, along with advanced analytics including AL/ML/NLP powered systems can be used to access/share/reuse patient data from historical clinical trials.

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Webinar

Delivering Data Driven Value

DataFAIRy Bioassay Annotation Pilot Project

In 2020, a team of scientists from AstraZeneca, Bristol Myers Squibb, Novartis, and Roche set forth to find a way to convert unstructured biological assay descriptions into FAIR information objects.

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Presentations

Delivering Data Driven Value

A Stepwise Approach to Fair Aligned Semantic Annotation Within eLNs: Phase 1 – ADME and PD Workflow

Phase 1 - ADME and PD Workflow to semantically tag unstructured text

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News Article

Delivering Data Driven Value

Computational approaches to therapeutic antibody design: established methods and emerging trends

Due to their binding versatility, antibodies are currently the largest class of biotherapeutics, with five monoclonal antibodies ranked in the top 10 blockbuster drugs. Computational advances in protein modelling and design can have a tangible impact on antibody-based therapeutic development.

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Toolkit

Core Projects

ABvance Toolkit

The Pistoia Alliance AbVance initiative was focused on two workstreams; (I) advancing the state of the art in antibody complex modelling for drug discovery, and (II) building better predictive models to address ‘developability’ risk

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Journal Article

Delivering Data Driven Value

Towards Virtual Knowledge Broker Services for Semantic Integration of Life Science Literature and Data Sources

This article presents a perspective on semantics-driven data integration in the life sciences, highlighting how the SESL pilot project uses open semantic web standards to unify structured and unstructured public and proprietary data, enhancing access, reducing redundancy, and enabling cross-domain collaboration through a precompetitive consortium.

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