Hear Erik Schultes from @GOFAIRofficial (part of the Linked Data Community of Practice seminar schedule, organized by AstraZeneca) discuss what are the FAIR principles and give examples of their implementation.
Resource Tag: Delivering Data Driven Value
HELM is included in the technical guidance for ISO 11238
This document provides guidelines for implementing ISO 11238. This document is developed in response to a worldwide demand for guidance on the implementation of internationally harmonized specifications for medicinal products. It is one of a group of four implementation guides for a total of five ISO standards which together provide the basis for the unique identification of medicinal products.
Collecting Reaction Incident Information: Engaging the Community in Sharing Safety Learnings
Every day unexpected incidents happen in the laboratory and each such incident provides experience that supports the learning process. The basic premise of the Chemical Safety Library (CSL) project, undertaken by the Pistoia Alliance, is that these learnings should be shared with the wider community so that everyone who works in a lab has an opportunity to learn from those unexpected reaction outcomes. In this paper, we will discuss the importance of community sharing to promote safety, the conceptualization and implementation of the CSL project, the results since the launch of the CSL service, next steps, and some thoughts on how this data collection could be leveraged in the future.
HELM Software for Biopolymers
Hierarchical Editing Language for Macromolecules (HELM version 2.0) is a molecular line notation similar to SMILEs but specifically for communicating and managing biopolymer structures. The HELM project, part of the Pistoia Alliance nonprofit organization, has been tasked to develop and promote HELM as a global exchange format and recently released version 2.0 of the specification. Here we will describe the specifics of the HELM v2.0 notation along with the large ecosystem of software to support HELM-based structure management. We will highlight a recent open-source software and database for HELM monomers and a new, simpler approach to deploying a large complicated molecular management system.
Pistoia Alliance Chemical Safety Library Datathon Kickoff
Hear about the Chemistry Safety Library Datathon, how to enter a previous lab incident into the tool and hear about the prizes on offer over the next 2 weeks of the datathon.
Ontologies Mapping for More Effective Data Integration and Knowledge Management
IDMP: It’s All About the Patient – Enhancing Patient Safety Through Improved R&D Information Exchange
Ontologies Guidelines for Best Practice and a Process to Evaluate Existing Ontologies Mapping Tools and Algorithms
This extended abstract presents an ongoing work by the Pistoia Alliance Ontologies Mapping project to develop user requirements for an ontologies mapping service.
Introducing the Disease and Phenotype OAEI Track
The paper introduces a new evaluation track aimed at aligning medical ontologies related to diseases and phenotypes, to support automated mapping and improve interoperability in biomedical research.
HELM for Bioregistration
GSK will be making use of the Pistoia Alliance’s Hierarchical Editing
Language for Macromolecules (HELM) notation to represent therapeutic
large molecules in its bio-registration system, facilitated by the deployment
of Dassault Systèmes BIOVIA’s Biological Registration solution. GSK
scientists at sites around the world will use the system.