Delivering Data Driven Value

Ready, Set, GO FAIR


Hear Erik Schultes from @GOFAIRofficial (part of the Linked Data Community of Practice seminar schedule, organized by AstraZeneca) discuss what are the FAIR principles and give examples of their implementation.

HELM is included in the technical guidance for ISO 11238

This document provides guidelines for implementing ISO 11238. This document is developed in response to a worldwide demand for guidance on the implementation of internationally harmonized specifications for medicinal products. It is one of a group of four implementation guides for a total of five ISO standards which together provide the basis for the unique identification of medicinal products. 

Collecting Reaction Incident Information: Engaging the Community in Sharing Safety Learnings

Every day unexpected incidents happen in the laboratory and each such incident provides experience that supports the learning process. The basic premise of the Chemical Safety Library (CSL) project, undertaken by the Pistoia Alliance, is that these learnings should be shared with the wider community so that everyone who works in a lab has an opportunity to learn from those unexpected reaction outcomes. In this paper, we will discuss the importance of community sharing to promote safety, the conceptualization and implementation of the CSL project, the results since the launch of the CSL service, next steps, and some thoughts on how this data collection could be leveraged in the future.

HELM Software for Biopolymers

Hierarchical Editing Language for Macromolecules (HELM version 2.0) is a molecular line notation similar to SMILEs but specifically for communicating and managing biopolymer structures. The HELM project, part of the Pistoia Alliance nonprofit organization, has been tasked to develop and promote HELM as a global exchange format and recently released version 2.0 of the specification. Here we will describe the specifics of the HELM v2.0 notation along with the large ecosystem of software to support HELM-based structure management. We will highlight a recent open-source software and database for HELM monomers and a new, simpler approach to deploying a large complicated molecular management system.

Introducing the Disease and Phenotype OAEI Track

The paper introduces a new evaluation track aimed at aligning medical ontologies related to diseases and phenotypes, to support automated mapping and improve interoperability in biomedical research.

HELM for Bioregistration

GSK will be making use of the Pistoia Alliance’s Hierarchical Editing
Language for Macromolecules (HELM) notation to represent therapeutic
large molecules in its bio-registration system, facilitated by the deployment
of Dassault Systèmes BIOVIA’s Biological Registration solution. GSK
scientists at sites around the world will use the system.