Pistoia Alliance Webinar: Generative Therapeutics Design: Accelerating Drug Discovery with AI & Machine Learning


JavaScript Disabled
JavaScript Disabled
(Date and time are shown in your browser's local time zone)

Event Type

What: Generative Therapeutics Design: Accelerating Drug Discovery with AI and Machine Learning


When: October 19, 4 PM BST / 11 AM EDT / 8 AM PDT

Register Today


Webinar Summary

The application of Artificial Intelligence/Machine Learning (AI/ML) methods in drug discovery are maturing and their utility and impact is likely to permeate many aspects of drug discovery. Numerous methods, however, utilize structure-activity relationship (SAR) data without explicit use of 3D structural information of the ligand protein complex. Gilead is using BIOVIA’s Generative Therapeutics Design solution (GTD) to take advantage of 3D structural models, i.e. pharmacophoric representation of ligand protein interaction as well as typical docking/scoring steps. Using Gilead’s SAR data set pertaining to the discovery of spleen tyrosine kinase (SYK) inhibitors Entospletinib and Lanraplenib they found that common types of problems in medicinal chemistry can be effectively addressed via GTD.



Ready to Get Involved?

There has never been a more important time to collaborate to innovate as an industry! If you would like to find out more about the benefits of Pistoia Alliance membership and how you can get involved with all the different initiatives we run, please send an email to Membership@PistoiaAlliance.org.