Streamline Data Exchange for Complex Bioassay Assay Data and High-Dimensional Biomarker Data

Date Submitted: Aug, 2023

Idea Originator:  Mark McCreary, Genentech

Strategic Priority: Deliver Data-Driven Value at Scale


Problem Statement

While standards exist for complex bioassay data and high-dimensional biomarker data they are not implemented in a consistent manner and there is no general agreement on a minimal set of metadata that should be shared between CROs, labs and pharmaceutical companies.  The lack of consistent implementation of standards increases the complexity of data exchange between labs, CROs and pharmaceutical companies resulting in inefficiencies in data use and data interoperability, and higher costs to acquire, transform, and make use of relevant data in meaningful ways.


Idea Proposal and Value Proposition

The idea is to define consistent and standard data and metadata formats for complex bioassay data and high-dimensional biomarker data, which could serve as a baseline framework for data exchange across the biomedical industry.
This would benefit labs, CROs, and pharmaceutical companies by streamlining data exchange between labs, CROs and pharmaceutical companies, and enable data sharing of harmonized datasets within and between companies. This would also benefit researchers who use the data by giving more context to the data, improve data findability/discoverability, and enable integration of datasets.
Importantly, as the industry moves towards the utilization of advanced analytics AI/ML technologies, it will be important to have harmonized datasets for training and enabling AI/ML method development. By creating and aligning on standards during the data generation process, it will reduce data management and curation costs downstream and speed up the pace at which teams can access and use these data.

Critical Success Factors
  • Securing the interest of 5-6 pharmaceutical companies, labs and CROs willing to invest in the project, define use cases and prioritize data types.
  • Determine a process for maintaining, governing, and expanding the standards.