The Pistoia Alliance HELM project started almost two years ago in December 2012 when David Klatte proposed that the Pistoia Alliance help open source a technology first developed for internal use at Pfizer. That technology was HELM and it enabled the representation of complex macromolecules. The Pistoia Alliance membership enthusiastically embraced the idea and the HELM project was born.
The Analysome concept was initiated by the U-BIOPRED team and supported by the Pistoia Alliance. Although developed as a pre-project assessment exercise, the outputs delivered by the Pistoia Alliance provided many of the benefits of a full-scale project and included the creation of a fully functional prototype.
The November 2014 edition of the Pistoia Alliance newsletter, Innovation in Action, is available to download as a PDF document.
The 2014 Pistoia Alliance Annual Report is available to download as a PDF document.
The presentation and recording from the Cloud Security for Life Science R&D WEBINAR held on Monday 20th October 2014 are available here.
A case study on CSCS from Novartis.
Today begins a new era for the Pistoia Alliance. With the launch of the Interactive Project Portfolio Platform (IP3) we are embracing a new level of openness, access, and transparency around the Pistoia Alliance’s idea-to-project process.
HELM addresses a problem at the root level of drug discovery. Pharmaceutical and biotech companies are looking at increasingly complex molecules in the search for new therapeutics, testing out RNA- and peptide-based compounds that tap directly into cellular pathways.
The proposal for the CSCS Expert Community originated from the Pistoia Alliance CSCS Project, which ran from November 2012 – April 2014. The CSCS Project completed successfully with the delivery of two commercially available Controlled Substance Compliance Services by ChemAxon/Patcore and Scitegrity.