HELM Phase 1 Exceeded Expectations

The Pistoia Alliance HELM project started almost two years ago in December 2012 when David Klatte proposed that the Pistoia Alliance help open source a technology first developed for internal use at Pfizer. That technology was HELM and it enabled the representation of complex macromolecules. The Pistoia Alliance membership enthusiastically embraced the idea and the HELM project was born.

Analysome Completed, Prototype Published

The Analysome concept was initiated by the U-BIOPRED team and supported by the Pistoia Alliance. Although developed as a pre-project assessment exercise, the outputs delivered by the Pistoia Alliance provided many of the benefits of a full-scale project and included the creation of a fully functional prototype.

HELM takes on indescribable biology

HELM addresses a problem at the root level of drug discovery. Pharmaceutical and biotech companies are looking at increasingly complex molecules in the search for new therapeutics, testing out RNA- and peptide-based compounds that tap directly into cellular pathways.

Report on the CSCS Expert Community Kick-off Meeting

The proposal for the CSCS Expert Community originated from the Pistoia Alliance CSCS Project, which ran from November 2012 – April 2014.  The CSCS Project completed successfully with the delivery of two commercially available Controlled Substance Compliance Services by ChemAxon/Patcore and Scitegrity.